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Teacher Reading about Insulin & Glucagon (optional resource for your information):

• An Introduction to Secretion of Insulin & Glucagon

1. Ask students, now that they know how body systems are compromised  by diabetes, what do they think happened to people with diabetes prior to insulin medicines?
2. Play the History of Insulin Part I, then ask students:
1. What used to happen to people with diabetes before insulin?
2. What organ was found to be responsible for insulin production?
3. What were early treatment options that doctors devised for people with diabetes? 
3. Play the History of Insulin Part II, then ask students:
1. The pancreases of what two animals were originally used to extract insulin?
2. What was the primary problem with initial insulin extracts?
3. After the discovery of purified insulin, why wasn't everyone with diabetes cured?
4. Play the History of Insulin Part III, then ask students: 
1. Is insulin still being made using the pancreases of animals?
2. How is insulin made today? 

Let students know that in the next lesson, they will be creating insulin in a virtual laboratory using today's DNA technology.  

NOTE:  The video clips are sponsored by Novo Nordisk; to avoid their company plugs at the end of each clip, stop them at the following times:

• Part I: stop player at 07:19
• Part II: stop player at 07:03
• Part II: stop player at  08:43

• History of Insulin Part I
• History of Insulin Part II
• History of Insulin Part III